BRCA1 -mutated ovarian cancer with skin metastasis: a case report.

Obstetrics & gynecology science(2017)

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摘要
The major risk factor for ovarian cancer (OC) is mutation of the or DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that - and -mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of -mutated OCs is limited. Herein, we describe a case of OC with a mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.
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关键词
BRCA mutation,Ovarian neoplasms,Skin metastases
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