Can metabolomic profiling predict response to therapy?
NATURE REVIEWS RHEUMATOLOGY(2018)
摘要
Shifts in cellular metabolism are central to activation, differentiation and proliferation of inflammatory cells and can contribute to the pathogenesis of inflammatory diseases. Integrating metabolomics data with other omics data is a major challenge but might enable clinicians to stratify stages of disease and response to therapy in patients with rheumatoid arthritis.
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关键词
Biological therapy,Metabolomics,Rheumatoid arthritis,Medicine/Public Health,general,Rheumatology
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