Lipocalin-2 in Stroke.

Wen-Hai Chou,Guona Wang,Varun Kumar,Yi-Chinn Weng

Neuro : open journal（2015）

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摘要

Stroke is a leading cause of adult disability in the United States. However, limited number of molecularly targeted therapy exists for stroke. Recent studies have shown that Li-pocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and hemorrhagic strokes. This review is an attempt to summarize some LCN2-related research findings and discuss its role in stroke.

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关键词

24p3,Biomarker,Lipocalin-2,NGAL,Neutrophil,PKC,Phosphorylation,Reperfusion injury,Stroke

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