Integrated analysis of long non-coding RNAs and mRNAs associated with peritendinous fibrosis.

•RNA-seq identified 20646 lncRNAs in peritendinous tissues.•A total of 219 lncRNAs and 3403 mRNAs were differentially expressed during fibrosis progression.•Bioinformatics analysis revealed enriched functions of dysregulated mRNAs.•Possible lncRNA-mRNA interactions were examined using a co-expression network.•Silencing of dnm3os prevented profibrotic changes in primary tenocytes.