TOPAS: network-based structural alignment of RNA sequences
BIOINFORMATICS, pp. 2941-2948, 2019.
Motivation: For many RNA families, the secondary structure is known to be better conserved among the member RNAs compared to the primary sequence. For this reason, it is important to consider the underlying folding structures when aligning RNA sequences, especially for those with relatively low sequence identity. Given a set of RNAs with ...More
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