Tri-Block Copolymer Nanoparticles Modified with Folic Acid for Temozolomide Delivery in Glioblastoma.

Soraya Emamgholizadeh Minaei,Samideh Khoei,Sepideh Khoee,Mohammad Reza Karimi

The International Journal of Biochemistry & Cell Biology（2019）

引用 33|浏览35

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摘要

In the present study, Folic Acid (FA) ligand was used to functionalize Temozolomide-loaded Poly (ethylene Glycol)–Poly (Butylene Adipate)–Poly (ethylene Glycol)-coated magnetite nanoparticles (TMZ-SPION-PEG-PBA-PEG) for targeted chemotherapy of glioma cells.

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关键词

Glioblastoma multiforme,Temozolomide,Drug delivery,Folic acid,Nanoparticles

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