Overexpression of TONSL might be an independent unfavorable prognostic indicator in hepatocellular carcinoma.

Bin Yu,Youming Ding,Xiaofeng Liao,Changhua Wang,Bin Wang,Xiaoyan Chen

Pathology - Research and Practice（2019）

引用 11|浏览8

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摘要

TONSL holds promise for serving as a prognostic biomarker for HCC. DNA amplification, hypomethylation and miR-133b downregulation could be the mechanisms associated with TONSL upregulation in HCC. TONSL might function as an oncogene via cell cycle regulation pathways in HCC.

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关键词

Hepatocellular carcinoma,TONSL,Prognosis,miR-133b

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