Inverted Variant of Takotsubo Syndrome Caused by Inhaled Adrenergic Beta-2 agonists.

Takotsubo syndrome (TS) was initially described with a classic pattern of LV apical akinesis and accounts for around 75-80% of cases. Variants including inverted Takotsubo (also known as basal variant) can affect other areas of the myocardium.Several physiopathological mechanisms have been implicated. Catecholamine-induced cardiotoxicity is one of the most supported theories, while other triggers, including excessive use of inhaled beta-2 agonists, have also been described.Treatment of TS is mainly symptomatic and conservative and frequently leads to rapid resolution and LV function recovery.