Vitamin D supplementation of 4000 IU daily and cardiac function in patients with advanced heart failure: The EVITA trial

A. Zittermann, J.B. Ernst,S. Prokop, U. Fuchs, A. Gruszka,J. Dreier,J. Kuhn,C. Knabbe,H.K. Berthold, I. Gouni-Berthold,S. Pilz, J.F. Gummert, L. Paluszkiewicz

International Journal of Cardiology（2019）

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摘要

•The effect of vitamin D on cardiac function is hotly debated but available data are inconclusive.•We investigated the effect of a daily vitamin D3 supplement of 4,000 IU for three years on cardiac function.•Vitamin D supplementation may not improve cardiac function in all patients with heart failure, but probably in patients aged ≥ 50 years.

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关键词

Vitamin D,Heart failure,Left ventricular ejection fraction,Randomized controlled trial,Echocardiography

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Vitamin D supplementation of 4000 IU daily and cardiac function in patients with advanced heart failure: The EVITA trial

Vitamin D supplementation of 4000 IU daily and cardiac function in patients with advanced heart failure: The EVITA trial