Hsa-miR-375 is a predictor of local control in early stage breast cancer

Franz Zehentmayr,Cornelia Hauser-Kronberger,Barbara Zellinger,Falk Hlubek,Claudia Schuster,Ulrich Bodenhofer,Gerd Fastner,Heinz Deutschmann,Philipp Steininger,Roland Reitsamer,Thorsten Fischer,Felix Sedlmayer

Clinical Epigenetics（2016）

引用 45|浏览24

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摘要

A long-term analysis by the Early Breast Cancer Trialist Group (EBCTG) revealed a strong correlation between local control and cancer-specific mortality. MicroRNAs (miRs), short (20–25 nucleotides) non-coding RNAs, have been described as prognosticators and predictors for breast cancer in recent years. The aim of the current study was to identify miRs that can predict local control after breast conserving therapy (BCT) in early stage breast cancer.

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关键词

MicroRNAs,hsa-miR-375,Early stage breast cancer,Local control,Predictive markers

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