VITAMIN D3 LEVELS MODULATE CXCR4+ CIRCULATING PROGENITOR CELL COUNTS

Salim Hayek,Yi-An Ko,Ibhar Al Mheid,Kareem Hosny,Hina Ahmed,Brandon Gray,Keyur Patel,Iraj Hesaroieh,Greg S. Martin,Jinhee Kim,Edmund K. Waller,Arshed A. Quyyumi

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2016）

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摘要

The role of 1,25-dihydroxy-vitamin D3 (VitD3) in cardiovascular disease remains controversial. Vitamin D receptors on progenitor cells (PCs) promote maturation and vascular repair by inducing SDF1 expression and homing of CXCR4+ angiogenic myeloid cells. Whether VitD3 levels modulate circulating PCs

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