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Transition from LDL apheresis to evolocumab in heterozygous FH is equally effective in lowering LDL, without lowering HDL cholesterol

Knut Tore Lappegård,Terje Enebakk,Hilde Thunhaug,Anders Hovland

Atherosclerosis（2016）

Cited 16|Views8
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Abstract
•LDL apheresis is effective in reducing LDL cholesterol and Lp(a).•HDL cholesterol is also reduced during LDL apheresis.•Switching from LDL apheresis to PCSK9 inhibition maintain the LDL lowering effect.•PCSK9 inhibition does not lower HDL cholesterol.
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Key words
Familial hypercholesterolemia,LDL-apheresis,PCSK9 inhibitors
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