The Genetics of Gilles De La Tourette Syndrome: a Common Aetiological Basis with Comorbid Disorders?

Iordanis Karagiannidis,Fotis Tsetsos,Shanmukha Sampath Padmanabhuni,John Alexander,Marianthi Georgitsi,Peristera Paschou

Current behavioral neuroscience reports（2016）

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摘要

Gilles de la Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by multiple motor and vocal tics, commonly associated with attention deficit hyperactivity disorder (ADHD), obsessive–compulsive disorder (OCD) and autism spectrum disorders (ASDs). Here, we summarize and discuss evidence pointing to a shared genetic basis among TS, OCD, ADHD and ASD.

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关键词

Gilles de la Tourette syndrome,Genetics,Autism spectrum disorders,Attention deficit hyperactivity disorder,ADHD,Obsessive–compulsive disorder,OCD,Cross-disorder analysis

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