Highly Multiplexed Nanophotonic Probes With Independently Controllable Emitters For Optogenetic Brain Stimulation

Eran Segev,Laurent C. Moreaux,Jacob Reimer,Trevor M. Fowler,Derrick Chi,Wesley D. Sacher,Maisie Lo,Karl Deisseroth,Andreas S. Tolias,Andrei Faraon,Michael L. Roukes

2016 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO)（2016）

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摘要

We present visible-wavelength photonic probes that implement WDM method for delivery of complex illumination patterns with cellular-scale spatial resolution deep within brain tissue. Neuron activation is verified by extracellular electrical recordings, and by two-photon functional imaging.

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关键词

highly multiplexed nanophotonic probes,independently controllable emitters,optogenetic brain stimulation,visible-wavelength photonic probes,WDM method,complex illumination pattern delivery,cellular-scale spatial resolution,brain tissue,neuron activation,extracellular electrical recording,two-photon functional imaging

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