Reduced frequency of circulating CD4+CD25brightCD127lowFOXP3+ regulatory T cells in primary myelofibrosis

Margherita Massa, Rita Campanelli,Gabriela Fois,Laura Villani,Elisa Bonetti,Paolo Catarsi,Valentina Poletto,Gianluca Viarengo, Mara De Amici,Vittorio Rosti,Robert Peter Gale,Giovanni Barosi

Blood（2016）

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摘要

To the editor:Although primary myelofibrosis (PMF) is generally regarded as arising from a mutated stem or progenitor hematopoietic cell, immune dysregulation is common. For example, there are increased plasma levels of inflammatory cytokines and clinical and laboratory manifestations of

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