Altered Expression of IARS (isoleucyl-tRNA synthetase) Genes in Leukemia

Sanga Mitra,Arpa Samadder,Sayantani Sinha,Amitava Sengupta,Jayprokas Chakrabarti

Clinical Lymphoma, Myeloma & Leukemia（2016）

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摘要

Aminoacyl tRNA synthetase (ARS/ARS2) being housekeeping genes, over a long period no one considered that it could have connection to any disease. Alterations in the ARS/ARS2 genes that facilitate mRNA translation generate many diseases, including cancer.

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关键词

mRNA modification,Gene Expression Regulation,tRNA,RNA methylation

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