Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission

•Data from largest prevalence study of third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission.•Data on β-lactam minimum inhibitory concentration (MIC) distributions of 3GCREB.•Susceptibility testing of new and unconventional antimicrobials and combinations.•Susceptibility test results were correlated with molecularly characterised underlying resistance mechanisms.