Ultrastructural Comparison of Extraventricular and Central Neurocytomas

storage disorders. Indeed, a genetic test is still not available for some forms of neuronal ceroid lipofuscinosis, suspicion of which is a major indication for a skin biopsy. In summary, electron microscopy remains a critical diagnostic tool on the neuromuscular and neurodevelopmental disease units. Careful evaluation of skeletal muscle, peripheral nerve, and skin biopsies from selected patients makes significant contributions to the diagnosis of disease in these patients, who are often disabled by their illnesses, and to the well-being of their families that must care for them. Ultrastructural analysis guides physicians in selecting the most appropriate and costeffective confirmatory tests.