Proteomics-based network analysis characterizes biological processes and pathways activated by preconditioned mesenchymal stem cells in cardiac repair mechanisms

Dario Di Silvestre,Francesca Brambilla,Giovanni Scardoni,Pietro Brunetti,Sara Motta,Marco Matteucci,Carlo Laudanna,Fabio A. Recchia,Vincenzo Lionetti,Pierluigi Mauri

Biochimica et Biophysica Acta (BBA) - General Subjects（2017）

引用 9|浏览53

暂无评分

摘要

•MI determines random and heterogeneous molecular effects.•Untreated MI tissues showed a massive proteome remodeling.•Transepicardial injection of MSCp+ limits the infarct scar size and induces angiogenesis.•Transepicardial injection of MSCp+ induces the butanoate metabolism.•NCL and RAC1 are the main protein hubs of the MI tissues treated with MSCp+.

查看译文

关键词

MSCs,MSCp+,MSCp−,MI,MudPIT,LAD,Unt,Ctrl,LV,HBR,MRI,MS,MS/MS,nr,FDR,HSP,SpC,DAve,DCI,LDA,aSpC,GMPI,PBS,dep,hc-dep

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要