MRI and Genetic Damage: An Update

Purpose of Review Magnetic resonance imaging (MRI) is generally considered to be a safe imaging technology when compared to diagnostic tools utilizing ionizing radiation. Unlike ionizing radiation, for which the detrimental biological effects, such as DNA damage, are known and well established, the potential of MRI to directly or indirectly induce genetic alterations is still not evident. This review article summarizes recent findings in MRI research related to DNA damage. Recent Findings Applying different exposure conditions, several studies have examined the potential impact of MRI on DNA. While some authors reported increases in DNA damage, the largest studies and those with the highest field strength (up to 7 T) and highest exposure did not find a significant excess in DNA damage. Summary The debate about biological effects of MRI has been increasingly tackled over the last years, due to extended use of MRI systems in clinic and research. The balance of scientific evidence from available literature does not allow a final conclusion regarding any significant risk related to DNA damage induced by MRI. The risk and its impact on public health, if any, should be substantially small.