Performance of Afp-Based Hepatocellular Carcinoma Surveillance in Cirrhosis Patients with Cured Hcv

and in the hospital (death, length of stay, charges) with adjustment for age, gender, trauma center, teaching/nonteaching, and comorbidities.All estimates were weighted to be nationally representative.Results: We identified 115,789 cirrhotic and 36,411,043 non-cirrhotic patients who presented with a fall.Cirrhotic patients were older (mean age 61.9 vs 43.9, p<0.001) and mostly male (56% vs 44%, p<0.001).The unadjusted rate of injury among cirrhotics was lower (8.69%vs 9.38%, p<0.001) and remained so after adjustment (OR 0.50, CI 0.48-0.52).While patients with cirrhosis were less likely to experience injurious falls, their injury severity score was higher (4.22 vs 2.76, p<0.001) with increased odds ratio of major injuries such as intracranial hemorrhage, pelvic and femur fractures, and pneumothorax (Table1).Patients without cirrhosis, when injured, were more likely to be diagnosed with less-severe injuries (e.g.concussions, lower leg fractures).Cirrhosis was associated with increased risk of in-hospital death for those with falls with or without injury (Table 2).Both ED and hospital charges as well as length of hospital-stay were significantly higher patients with cirrhosis, irrespective of injury.Conclusion: Though patients with cirrhosis who present to the emergency department with falls are less likely to sustain injuries relative to non-cirrhotics, the fall itself is a marker of increased mortality risk.Furthermore, when injured, the severity and care utilization for cirrhotics is significantly higher. 1052