Sa1066 A Systematic Review Meta-Analysis of Prospective Studies: is Peroral Endoscopic Myotomy (poem) a Safe Procedure in Adult Patients with Achalasia?

Achalasia is a primary esophageal motility disorder characterized by failure of lower esophageal sphincter to relax in response to swallowing, along with loss of peristalsis of esophagus. Although surgical myotomy has been the mainstay treatment modality, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative.