PERIPHERAL BLOOD WT1 EXPRESSION REFINES PROGNOSTIC INFORMATION FOR MDS PATIENTS WITHIN THE IPSS-R RISK CATEGORIES VERY LOW, LOWAND INTERMEDIATE

Packed beds of monosized spherical particles in cylindrical confined walls are simulated using DigiDEM™, LIGGGHTS® and blender™. Parameter studies to characterise the influence of the cylinder-to-particle diameter ratio and the filling speed on mean bed porosity are conducted for all three approaches. It is shown that the results obtained for bed configuration are in agreement with experimental results. A clear trend illustrating the influence of filling speed on mean bed porosity is presented. Moreover, new insights on local packing structure are revealed.