Temperature and solvent dependent apparent thermodynamic behavior of 2-Mercaptomethyl Benzimidazole in pure and binary solvents from 283.15 K to 328.15 K

In this work, the solubility of 2-Mercaptomethyl Benzimidazole (MMB)in eight pure solvents (i.e., ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, ethyl acetate, acetonitrile and acetone) and two binary solvents (ethanol+ethyl acetate and 1-butanol+acetonitrile) were measured by a dynamic method at a temperature ranging from (283.15 to 328.15) K at atmospheric pressure. For the temperature range investigated, the solubility of MMB in all solvents increased with increasing temperature. The solubility in the pure solvents was well-correlated with the Apelblat equation, λh equation and NRTL equation. Further, RK model, together with Apelblat equation λh equation and NRTL equation were employed to correlate the solubility in binary solvents. Besides, the thermodynamic data in both pure and binary solvents (i.e., Gibbs energy, enthalpy, and entropy of mixing) were calculated by using the NRTL model to rank the solubility values in different pure solvents.