Preparation and reactivity of sterically encumbered organocatalysts and their use in the preparation of (S)-Pregabalin precursors

Mauro Cortigiani,Alberto Tampieri,Claudio Monasterolo,Andrea Mereu,Mauro F. A. Adamo

Tetrahedron Letters（2017）

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摘要

•A new class of organocatalysts based on a well-known and successful scaffold.•A new catalyst to perform synthesis of (S)-Pregabalin in higher enantioselectivity.•A new class of modularly built organocatalysts.

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关键词

4-Nitroisoxazoles,Phase transfer catalysis,Organocatalysis,(S)-Pregabalin

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