Probiotics supplementation and length of hospital stay in neonates with gastrointestinal surgery

International Journal of Surgery Protocols(2017)

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摘要
•Surgical stress causes disruption of the gut barrier and microbiome.•In neonates intestinal dysbiosis increases risk for feeding intolerance, prolonged use of parenteral nutrition, and post-operative infection.•Probiotics prevent bacterial overgrowth, promote gut barrier function, and modulate the local immune response.•Monitoring dynamic changes in microbiome of post-surgical infants who received probiotics and placebo will provide with important information about gut colonization.•This study will assess the effect of probiotics on length of hospital stay, duration of parenteral nutrition, and feed tolerance in post-surgical infants.
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关键词
CFU,EBM,GI,GA,NICU,NEC,RCT
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