Synthesis of N‐Substituted Condensed Tetrahydropyridine‐Based Enaminones via Palladium‐Catalyzed Intramolecular C–N Cross‐coupling

A number of -enaminones with secondary amino group (alkyl, cyclopropyl, and aryl) were prepared from corresponding -diketones. Two general protocols for their palladium-catalyzed intramolecular C-N cross-coupling were established to give corresponding N-substituted condensed tetrahydropyridines in good yields. The methodology is applicable for a wide variety of structural motifs. The work also extends the applicability of novel, recently established, palladium precatalysts to new substrates.