Optic Disc Detection from Fundus Photography Via Best-Buddies Similarity

Robust and effective optic disc (OD) detection is a necessary processing step in the research work of the automatic analysis of fundus images. In this paper, we propose a novel and robust method for the automated detection of ODs from fundus photographs. It is essentially carried out by performing template matching using the Best-Buddies Similarity (BBS) measure between the hand-marked OD region and the small parts of target images. For well characterizing the local spatial information of fundus images, a gradient constraint term was introduced for computing the BBS measurement. The performance of the proposed method is validated with Digital Retinal Images for Vessel Extraction (DRIVE) and Standard Diabetic Retinopathy Database Calibration Level 1 (DIARETDB1) databases, and quantitative results were obtained. Success rates/error distances of 100%/10.4 pixel and of 97.7%/12.9 pixel, respectively, were achieved. The algorithm has been tested and compared with other commonly used methods, and the results show that the proposed method shows superior performance.