Race/Ethnicity Influences Outcomes in Young Adults with Intracerebral Hemorrhage (S10.007)

Objective: The present study investigated the predictors of poor functional outcome among young intracerebral hemorrhage patients enrolled in the Ethnic/Racial Variations in Intracerebral Hemorrhage (ERICH) study. Background: Because of the increase in ICH incidence with age, risk factors and outcomes for older patients with this condition have been extensively characterized. On the other hand, studies that describe risk factors and outcomes in patients under age 50 with ICH have been limited to small, single-center, retrospective studies Design/Methods: The Ethnic/Racial Variations in Intracerebral Hemorrhage (ERICH) study is a prospective multi-center study of ICH among adult (age ≥18 years) non-Hispanic whites, non-Hispanic blacks, and Hispanics. The study recruited 1000 participants per racial/ethnic group. The present study utilized the subset of ERICH cases aged Results: Of the 3000 ICH cases enrolled in ERICH, 418 were studied (mean age 43 years, 69% male), of which 48 (12%) were white, 173 (41%) were black, and 197 (47%) were Hispanic. For supratentorial ICH, blacks (odds ratio [OR] 0.42, p=0.046) and Hispanics (OR 0.34, p=0.01) had better outcomes than whites after adjustment for other factors associated with poor outcome: age (p=0.04), baseline disability (p Conclusions: In young patients with supratentorial ICH, black and Hispanic race/ethnicity is associated with better functional outcomes, compared with white race. Additional studies are needed to identify the biological and social mediators of this association. Study Supported by: The ERICH study is supported by a grant from the National Institute of Neurological Disorders and Stroke (NINDS: U-01-NS069763). This report does not represent the official view of NINDS, the National Institutes of Health (NIH), or any part of the US Federal Government. No official support or endorsement of this article by NINDS or NIH is intended or should be inferred. Disclosure: Dr. Miyares has nothing to disclose. Dr Falcone has nothing to disclose. Dr. Leasure has nothing to disclose. Dr. Adeoye has nothing to disclose. Dr. Shi has nothing to disclose. Dr Kittner has nothing to disclose. Dr. Langefeld has nothing to disclose. Dr. Vagal has nothing to disclose. Dr. Sheth has nothing to disclose. Dr. Woo has nothing to disclose.