Different core-specific T cell subsets are expanded in chronic hepatitis C with advanced liver disease

Fabio C.O.F. Cachem,Aleida S. Dias,Clarice Monteiro,Gabriel Fernandes,Letícia Delphim,Felipe Tavares,Alessandra M.A. Maciel, Marcia M. Amendola-Pires,Carlos Eduardo Brandão-Mello,Regis Mariano Andrade,Cleonice A.M. Bento

Cytokine（2019）

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摘要

•IL-17+IL-6+ T-cells are elevated in HCV patients with advanced liver stiffness.•Lower percentage of CD39+ Tregs in HCV patients with advanced liver stiffness.•HCV-specific PD-1+ CD57+ T cells accumulate in patients with worse hepatic lesions.

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关键词

HCV,T cells,IL-17,IL-6

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