Social brain, social dysfunction and social withdrawal

Stefano Porcelli,Nic J.A. van der Wee,Steven J.A. van der Werff,Moji Aghajani,Jeffrey C. Glennon,Sabrina van Heukelum,Floriana Mogavero,Antonio Lobo, Francisco Javier Olivera,Elena Lobo, Mar Posadas,Juergen Dukart,Rouba Kozak, Estibaliz Arce,Arfan Ikram,Jacob Vorstman,Amy Bilderbeck,Ilja Saris,Martien J.H. Kas,Alessandro Serretti

Neuroscience & Biobehavioral Reviews（2019）

引用 212|浏览75

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摘要

•The human brain shows several levels of specialization for social stimuli processing.•Social brain could be affected by several neuropsychiatric disorders.•Mechanisms underlying social dysfunction are largely similar across disorders.•Social dysfunction and social withdrawal may represent a transdiagnostic domain.•A better understanding of their biological underpinnings may lead to new treatments.

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关键词

Social withdrawal,Neurobiology,Social brain,Social dysfunction,Social impairments,Social cognition,Social functioning,Schizophrenia,Alzheimer’s disease,Major depression disorder

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