Big Data Analysis Of Treatment Process Time For The Real-Time-Image Gated-Spot-Scanning Proton-Beam Therapy (Rgpt) System

We aimed to develop a real-time-image gated spot-scanning proton therapy (RGPT) system for moving tumors in organs such as liver, pancreas, lung, and prostate. When the spot-scanning technique is linked to gating, beam delivery time with gating can be longer than that without gating. To analyze the aspect of time, we quantitatively analyzed the treatment process time in our facility using big data obtained from patient treatment logs that contain >100,000 data points per day. Data from 92 patients, corresponding to 117 treatment plans executed from October 2016 to October 2017, were included in this study. To estimate treatment process time, we used data from the mechanical log (duration of irradiation) and the patient log (duration between patient walk-in to the treatment room before radiation therapy and patient walk-out from the treatment room post therapy). We used treatment planning data, including the disease site, target volume, delivered dose, and the number of layers and spots for each field. We evaluated the total treatment process time, patient load time, bone matching and marker matching time, beam delivery time, and patient unload time. Of the 70 treatment planning were used the RGPT system (liver: n = 33; pancreas: n = 4; lung: n =3; and prostate: n = 30). The mean and standard deviation (SD) of the total treatment process time for the RGPT system were 31.2 ± 8.1 min (load: 4.8 ± 1.7 min, bone matching: 6.3 ± 2.1 min, marker matching: 3.1 ± 1.1 min, beam delivery: 7.8 ± 5.5 min, equipment setting: 5.4 ± 1.6 min, and unload: 3.9 ± 2.3 min), while that for the without gating treatment exclude pediatric craniospinal irradiation (CSI) were 27.1 ± 7.9 min (load: 5.6 ± 2.3 min, bone matching: 7.8 ± 4.5 min, beam delivery: 4.0 ± 1.8 min, equipment setting: 5.6 ± 2.0 min, and unload: 4.2 ± 1.2 min), and that for pediatric (CSI) were 61.9 ± 16.0 min (load: 9.1 ± 8.0 min, bone matching: 18.0 ± 2.9 min, beam delivery: 12.2 ± 1.0 min, equipment setting: 14.6 ± 2.9 min, and unload: 8.0 ± 9.0 min). Our results using the big data approach show that the RGPT system can achieve acceptable treatment process time for clinical purposes.Abstract TU_29_3178; Table 1Treatment process [min]with RGPTwithout RGPTExclude Pediatric (CSI)Pediatric (CSI)Mean ± SD(n=70)Mean ± SD(n=40)Mean ± SD(n=7)Patient load4.8 ± 1.715.3%5.6 ± 2.320.5%9.1 ± 8.014.7%Bone matching6.3 ± 2.120.1%7.8 ± 4.528.8%18.0 ± 2.929.1%Maker matching3.1 ± 1.19.9%N.A. ± N.A.N.A.N.A. ± N.A.N.A.Beam delivery7.8 ± 5.524.9%4.0 ± 1.814.7%12.2 ± 1.019.7%Equipment setting5.4 ± 1.617.3%5.6 ± 2.020.5%14.6 ± 2.923.6%Patient unload3.9 ± 2.312.6%4.2 ± 1.215.5%8.0 ± 9.013.0%Total31.2 ± 8.1100.0%27.1 ± 7.9100.0%61.9 ± 16.0100.0% Open table in a new tab