NG-test Carba5 for rapid detection of carbapenemase-producing Enterobacterales from positive blood cultures.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(2019)

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摘要
The immunochromatographic assay, NG-test Carba 5 (NG Biotech), has been evaluated for detection of carbapenemase-producing Enterobacterales (CPE) from spiked blood cultures (n = 205). It detected and discriminated in less than 30 minutes KPC, IMP, VIM, NDM, and OXA-48-like producers with a sensitivity and specificity of 97.7% and 96.1%, respectively. Thus, it might help the rapid optimization of treatment of bloodstream infections due to CPE.
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关键词
IMP,KPC,NDM,OXA-48-like,VIM,immunochromatography,rapid diagnostic,septicemia
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