Overexpression of HIF-2α-Dependent NEAT1 Promotes the Progression of Non-Small Cell Lung Cancer through miR-101-3p/SOX9/Wnt/β-Catenin Signal Pathway.

Xiangjun Kong,Yue Zhao,Xinmeng Li,Zhenxia Tao,Mingming Hou,Hui Ma

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2019）

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摘要

NEAT1 up-regulation induced by HIF-2α over-expression could promote the progression of NSCLC under hypoxic condition. Moreover, NEAT1 also takes part in NSCLC progression via miR-101-3p/SOX9/Wnt/β-catenin axis.

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关键词

Hypoxia,NEAT1,NSCLC,SOX9,Wnt/β-catenin,miR-101-3p

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