Prenatal manganese and cord blood mitochondrial DNA copy number: Effect modification by maternal anemic status.

Allison Kupsco,Marco Sanchez-Guerra,Chitra Amarasiriwardena,Kasey J M Brennan,Guadalupe Estrada-Gutierrez,Katherine Svensson,Lourdes Schnaas,Ivan Pantic,Martha María Téllez-Rojo,Andrea A Baccarelli,Robert O Wright

Environment International（2019）

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摘要

•Mn in 3rd trimester blood and in cord blood was positively associated with mtDNA CN.•The relationship between 2nd trimester Mn and mtDNA CN was modified by anemia.•Mn in maternal blood at birth was not associated with cord blood mtDNA content.•Maternal anemia, serum ferritin, and MCV were not associated with mtDNA CN.

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关键词

Prenatal exposure,Manganese,Anemia,Iron deficiency,Mitochondria,Mitochondrial DNA

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