Impaired gonadal and somatic development corroborate vulnerability differences to the synthetic estrogen ethinylestradiol among deeply diverged anuran lineages.

•Environmentally relevant EE2-concentrations: clawed frogs, tree frogs, green toads.•Simultaneous flow-through-exposure, genetic sexing, morphology and histopathology.•Sex reversals and mixed sex previously shown; anatomical impairments of gonads.•Inter-species vulnerability differences in gonad and somatic development due to EE2.