Evaluation of an Fmri USPIO-based Assay in Healthy Human Volunteers.

Richard Baumgartner,William Cho,Alexandre Coimbra,Christopher Chen,Zaiqi Wang,Arie Struyk,Narayanaswamy Venketasubramanian,May Low, Cindy Gargano,Fuqiang Zhao,Donald Williams,Torsten Reese,Stephanie Seah,Dai Feng, Sonya Apreleva,Esben Petersen,Jeffrey L. Evelhoch

Journal of magnetic resonance imaging（2016）

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摘要

To present the testretest and contrast dose effect results of cerebral blood volume (CBV) functional MRI (fMRI) in healthy human volunteers using ferumoxytol (Feraheme), an ultrasmall‐superparamagnetic iron oxide (USPIO) nanoparticle.

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关键词

fMRI,ferumoxytol,cerebral blood volume,visual stimulation,drug development

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