Medium redesign for stable cultivation and high production of mevalonate by recombinant Methtylobacterium extorquens AM1 with mevalonate synthetic pathway

Lan-Yu Cui,Wei-Fan Liang,Wen-Liang Zhu,Ming-Yang Sun,Chong Zhang,Xin-Hui Xing

Biochemical Engineering Journal（2017）

引用 11|浏览6

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摘要

•A cheap, effective medium was developed for stable cell growth.•Cell-to-cell heterogeneity confirmed that the medium support stable cell growth.•The highest MEV titer productivity yet reported for AM1 was obtained.

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关键词

Methylobacterium extorquens AM1,Mevalonic acid,Stable growth,Methanol

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