Long-term pulmonary complications in perinatally HIV-infected youth.

William T Shearer,Denise L Jacobson,Wendy Yu,George K Siberry,Murli Purswani,Suzanne Siminski,Laurie Butler,Erin Leister,Gwendolyn Scott,Russell B Van Dyke,Ram Yogev,Mary E Paul,Ana Puga,Andrew A Colin,Meyer Kattan

The Journal of Allergy and Clinical Immunology（2017）

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摘要

Compared with HEU youth, HIV-infected youth demonstrated decreased reversibility of obstructive lung disease, which is atypical of asthma. This might indicate an early stage of chronic obstructive pulmonary disease. Follow-up into adulthood is warranted to further define their pulmonary outcomes.

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关键词

Pediatric HIV infection,asthma,asthma-COPD overlap syndrome,chronic obstructive pulmonary disease,immune imbalance (T(H)2 shift),obstructive and restrictive pulmonary disease,pulmonary complications of HIV infection,pulmonary function testing,reversibility of obstructive air flow with bronchodilators

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