Expedient chemoselective and catalyst-free synthesis of 3,3-difluorochroman-4-ones from o-hydroxyarylenaminones and Selectfluor

Chinese Chemical Letters(2018)

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摘要
An expedient and mild strategy for the synthesis of unconventional 2-(dimethylamino)-3,3-difluorochroman-4-one derivatives from o-hydroxyarylenaminones and Selectfluor was developed at room temperature under catalyst-free conditions. This method showed excellent chemoselectivity and great functional groups tolerance.
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关键词
Selectfluor,o-Hydroxyarylenaminones,Catalyst-free,Chroman-4-one,Fluorination reaction,Fluorine-contained compound
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