Smoking and interstitial lung diseases(ILDs)

Smoking is accepted as the cause of respiratory bronchiolitis-associated ILD (RB-ILD), desquamative interstitial pneumonia(DIP), pulmonary Langerhans cell histiocytosis(PLCH).It is also a risk factor for idiopathic pulmonary fibrosis(IPF). Aim: The aim of the study was to assess the smoking status (ever-smokers/never-smokers)(ES/NS) among ILDs(not sarcoidosis) patients(pts). Methods: The group of 131 consecutive ILDs pts admitted to our hospital were asked about smoking. Questionnaire was designed, data was recorded. Results: Among recruited pts (52±7y); 57 were male and 74 were female. There were 22(20ES/2NS)pts diagnosed as PLCH, 27(13ES/14NS) as hypersensitivity pneumonitis(HP),22(11ES/11NS) as connective tissue disease(ILD-CTD),17(9ES/8NS) as unclassifiable idiopathic interstitial pneumonia(UIIP),10(8ES/2NS) as granulomatosis with polyangiitis(GPA),7(6ES/1NS) as IPF, 10(4ES/6NS) as cryptogenic organising pneumonia(COP),3(2ES/1NS) idiopathic nonspecific interstitial pneumonia(NSIP), 2(2ES/0NS) as DIP, 2(1ES/1NS) as chronic eosinophilic pneumonia(CEP),1(0ES/1NS) as RBILD, 8(0ES/8NS) as lymphangioleiomyomatosis(LAM).In ES group 8 pts continue to smoke. Women smoked fewer cigarettes per day compared to men(14.6vs 17.7)p Conclusions: There were more smokers among pts with some ILDs. Passive smoking exposure in infancy could be a risk factor for some ILDs.