Development and validation of an HPLC-MS/MS method with QuEChERS extraction using isotopic dilution to simultaneously analyze chlordecone and chlordecol in animal livers

•Quick, Easy, Cheap, Effective, Rugged and Safe extraction method in liver samples.•Liquid chromatography tandem mass spectrometry method analysis.•Validated method according to NF V03-110 and the European Union guidelines.•Application of the method to field-collected liver samples.•Chlordecone metabolism can take place in liver of ruminant species.