Donor Specific Antibodies in Heart Transplantation: Do Clinicians Need to do Something Always?

Yasbanoo Moayedi, J.A. McCaughan,J. Duero Posada,Mosaad Alhussein,L.A. Goldraich,K. Runeckles,S. Fan,F. Foroutan, C. Manhliot,Stella Kozuszko,A.C. Alba,Anne I. Dipchand,K. Tinckam,Heather J. Ross

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2018）

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摘要

De novo donor specific antibodies (dnDSA) are associated with poor prognosis, increased rejection, coronary allograft vasculopathy (CAV), graft failure and mortality. This study sought to assess incidence of transient dnDSA and persistent dnDSA, and evaluate their impact on the risk of mortality and CAV in heart transplant patients

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heart transplantation,specific antibodies

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