Gene silencing of ZnT8 attenuates inflammation and protects pancreatic tissue injury in T1D

Hong Sun,Cunyu Li,Shufa Li,Xunhua Li,Jinguang Wang,Zhongqi Zhou,Mingtao Shao

Immunology Letters（2018）

引用 8|浏览6

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摘要

•ZnT8 shRNA attenuated specific CD8+ T cell activation and cytotoxicity.•ZnT8 shRNA protected glucose tolerance and pancreatic tissue injury in NOD mice.•RNAi provides a novel therapeutical clue in T1D.

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关键词

ZnT8,Inflammation,Pancreatic tissue injury,T1D

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