Probiotics in IBD: Combining in vitro and in vivo models for selecting strains with both anti-inflammatory potential as well as a capacity to restore the gut epithelial barrier

Journal of Functional Foods(2018)

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摘要
•Selected strains exhibited different in vitro properties.•L. acidophilus was the most potent to restore the epithelial barrier function.•L. acidophilus CMUL067 limited colitis in mice by restoring the barrier integrity.•Combining in vitro and in vivo models allowed selection of promising strains for IBD.
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关键词
Probiotics,Inflammatory bowel disease,Colitis,Intestinal permeability
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