Multiple TOF/TOF Events in a Single Laser Shot for Multiplexed Lipid Identifications in MALDI Imaging Mass Spectrometry

International Journal of Mass Spectrometry(2019)

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摘要
•Multiple TOF/TOF events in each laser shot enable the simultaneous identification of multiple PC lipids in rat brain tissue.•Separation of precursor ions in TOF-1 allows for differentiation of isomeric fragment ions from different precursor ions.•Multiplexed imaging MS/MS allows the acquisition of complete fragment ion spectra for multiple precursor ions per laser shot.
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关键词
Multiplexed,MS/MS,Lipid,MALDI,Imaging mass spectrometry
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