ApoA-1 is oxidized in abdominal aortic aneurysm and promotes dysfunctional HDLs

D. Martínez lópez,L. Cedo,Emilio Camafeita, R. Montero Roldan,Inmaculada Jorge,Elena Burillo,F. Blanco vaca, L. Blanco Colio,Jesús Egido, J. Baptiste Michel,Jesús Vázquez,J. Escola Gil, J. Martín Ventura

ATHEROSCLEROSIS（2018）

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摘要

Aim: ApoA1, the main constitutive protein of high-density lipoproteins (HDLs), is prone to oxidative modifications during is outward transport through the arterial wall, which can lead to dysfunctional HDLs. We analyzed whether ApoA1 is oxidized in abdominal aortic aneurysm (AAA) patients and the effect on HDL functionality.

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关键词

abdominal aortic aneurysm,abdominal aortic,dysfunctional hdls

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