A case of pembrolizumab-induced autoimmune haemolytic anaemia with polymyalgia rheumatica

European Journal of Cancer(2018)

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摘要
Checkpoint inhibitors are recent therapies against cancer, and their indications are currently undergoing rapid expansion. However, these treatments unleash immune activation that triggers potential autoimmune side-effects. Such cases are reported but remain rare and misdiagnosed. We report the case of a patient treated with pembrolizumab, who developed autoimmune haemolytic anaemia (AIHA) and polymyalgia rheumatica (PMR). Letter to the editor: Comments on ‘A case of pembrolizumab-induced autoimmune haemolytic anaemia with polymyalgia rheumatica’European Journal of CancerVol. 111PreviewWe read with interest the report by Robilliard et al. [1] of a pembrolizumab-induced immune-related adverse event (irAE). We applaud them for bringing attention to polymyalgia rheumatica (PMR) as a rheumatic irAE after immune checkpoint inhibitor therapy and would like to add some comments and conclusions. Full-Text PDF
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关键词
polymyalgia rheumatica,autoimmune,haemolytic anaemia,pembrolizumab-induced
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