Disrupting the hippocampal Piwi pathway enhances contextual fear memory in mice.

Laura J Leighton,Wei Wei,Paul R Marshall,Vikram Singh Ratnu,Xiang Li,Esmi L Zajaczkowski,Paola A Spadaro,Nitin Khandelwal,Arvind Kumar,Timothy W Bredy

Neurobiology of Learning and Memory（2019）

引用 24|浏览33

暂无评分

摘要

•Several members of the Piwi pathway are expressed in the adult hippocampus.•Combined knockdown of Piwil1 and Piwil2 lead to enhanced context fear memory.•The Piwi pathway is involved in the control of plasticity-related gene expression in the adult mammalian brain.

查看译文

关键词

Learning,Memory,Noncoding RNA,Epigenetics,Molecular biology,Plasticity

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要