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Programming a Split G-quadruplex in a DNA Nanocage and Its Microrna Imaging in Live Cells

Yanyan Yu,Yao Zhou, Min Zhu,Mingkai Liu,Hongyan Zhu,Yong Chen,Gaoxing Su,Wei Chen,Huaping Peng

Chemical communications（2019）

Cited 7|Views7
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Abstract
A novel approach to program target-responsive devices by incorporating the split G4 motifs in a DNA nanocage has been developed. The rigid prism outcompetes the flexible one in reaction kinetics and signal/background ratios, which can be easily internalized by cells and successfully applied in microRNA imaging in live cells.
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